Lili Zhou, MD, PhD

Professor
National Clinical Research Center for Kidney Disease
State Key Laboratory of Organ Failure Research
Division of Nephrology, Nanfang Hospital, Southern Medical University

Dr. Lili Zhou’s research interests include pathogenesis of renal fibrosis after injury, senescence mechanism of renal fibrosis and Wnt/β-catenin signaling and immunology with kidney disease. 

She earned her bachelor and master degree of Clinical Medicine and nephrology respectively in Dalian Medical University and PhD degree in Southern Medical University. During 2011 to 2013, she got her post-doctoral training in University of Pittsburgh, School of Medicine. After that, she then works as the associate professor and researcher in nephrology department of Nanfang Hospital and acts as the principle investigator at two national platforms namely National Clinical Research Center of Kidney Disease and State Key Laboratory of Organ Failure Research.

Currently, Dr. Zhou belongs to the Ad hoc Reviewer for peer-reviewed Journals such as American Journal of Physiology-Renal Physiology, BioMed Research International, Current Nutrition & Food Science, Experimental and Therapeutic Medicine. She has been the member of Guangdong special talent plan young talent with scientific and technological innovation, member of Innovative Research Group of National Natural Science Foundation of China and Distinguished Young Talents in Higher Education of Guangdong province.

Selected Research and Publications

1. Luo CW, Zhou S, Zhou ZM, Liu YH, Yang L, Liu JF, Zhang YF, Li HY, Liu YH, Hou FF, Zhou LL. Wnt9a promotes renal fibrosis by accelerating cellular senescence in tubular epithelial cells. J Am Soc Nephrol. 2018 Apr; 29(4):1238-1256.

2.Mo HY, Wu QY, Miao JH, Luo CW, Hong X, Wang YP, Tang L, Hou FF, Liu YH, Zhou LL. Chemokine Receptor CXCR4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte Injury. Antioxid Redox Sign. 2017 Aug 20; 27(6):345-362.  

3.Zhou LL, Liu YH. Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease. Nat Rev Nephrol, 2015 Sep;11(9):535-45.

4.Zhou LL, Li YJ, He WC, Zhou D, Tan RJ, Nie J, Hou FF, Liu YH*. Mutual antagonism of WT1 and β-catenin dictates podocyte health and disease. J Am Soc Nephrol, 2015, 26(3):677-691. 

5.Zhou LL, Li YJ, Hao S, Zhou D, Tan RJ, Nie J, Hou FF, Kahn M, Liu YH. Multiple genes of the renin-angiotensin system are novel targets of Wnt/β-catenin signaling. J Am Soc Nephrol, 2015, 26(1): 107-120. 

6. Zhou LL, Li YJ, Zhou D, Tan RJ, Liu YH. Loss of Klotho contributes to kidney injury by de-repression of Wnt/β-catenin signaling. J Am Soc Nephol, 2013, 24(5): 771-785.