Jing Nie  MD., PhD

Professor
Deputy Director of the State Key Laboratory of Organ Failure Research of the Ministry of Education
National Clinical Research Center for Kidney Disease
Division of Nephrology, Nanfang Hospital,Southern Medical University

Professor of medicine and MD tutor at Southern Medical University. Dr. Nie earned her PhD degree from Kochi University in Japan in 1999. After that, she went on to her 5-year postdoctoral research at University of Toronto in Canada. Since 2004, Dr.Nie has served as a member of the faculty of nephrology department successively at Sun Yat-Sen University and at Southern Medical University. Dr. Nie has obtained a number of research grants including the National Outstanding Young Scientist Fund from National Natural Science Foundation of China.

Dr. Nie’s research focus on the pathogenesis and prevention strategies of chronic kidney diseases and is conducted from three aspects including risk factors, renal intrinsic cell injury mechanisms, and drug lead compounds. She has published more than 50 papers on peer-reviewed journals including J Am Soc Nephrol and Kidney Int.

More about Jing Nie
Education
Kochi University 1999

Fellowships
State Key Program of National Natural Science of China,2017
Science and Information Technology of Guangzhou Key Project,2014
National Science Fund for Outstanding Young Scholars,2013
Nature and Science Foundation of China,2011

Selected Research and Publications
1.Chang XY, Zhen X, Liu JX, Ren XM,Hu Z,Zhou ZM,Zhu FX,Ding K,Nie J.   The antihelmenthic phosphate niclosamide impedes renal fibrosis by inhibiting homeodomain-interacting protein kinase 2 expression. Kidney International. 2017 Mar 16.

2.Wan J, Hou XY, Zhou ZM, Geng J,Tian JW,Bai XY,Nie J.WT1 ameliorates podocyte injury via repression of EZH2/β-catenin pathway in diabetic nephropathy. Free Radical Biology & Medicine. 2017.108:280-299. 

3.Long YJ, Zhen X, Zhu FX,Hu Z,Lei WJ,Li S,Zha Y,Nie J.  Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury. International Journal of Biological Sciences. 2017.13(2):219-231. 

4.Ai J, Nie J, He JB, Guo Q, Li M, Lei Y, Liu YH, Zhou ZM, Zhu FX, Liang M, Cheng YX, Hou FF.GQ5 hinders renal fibrosis in obstructive nephropathy by selectively inhibiting TGF-β-induced Smad3 phosphorylation. J Am Soc Nephrol. 2015.26(8):1827-1838. 

5.Guo Zhang, Xia Chen1, Fanghua Qiu, Fengxin Zhu, Wenjing Lei, Jing Nie . A novel interaction between SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1-engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility. J Biol Chem 2014 289(33): 23112-22 

6.Cao W, Xu J, Zhou ZM, Wang GB, Hou FF, Nie J.   Advanced oxidation protein products activate intrarenal renin-angiotensin system via a CD36-mediated, redox-dependent pathway. Antioxid Redox Sign. 2013.18(1):19-35. 

7.Li Li Zhou, Wei Cao, Chao Xie, Jianwei Tian, Zhanmei Zhou, Qiugen Zhou, Ping Zhu, Aiqing Li, Youhua Liu, Toshio Miyata, Fan Fan Hou, Jing Nie. The receptor of advanced glycation end products (RAGE) plays a central role in advanced oxidation protein products-induced podocyte apoptosis. Kidney Int. 2012; 82: 759-770.