Di Xie., MD, PhD

Associate Chief Physician
National Clinical Research Center for Kidney Disease
Division of Nephrology, Nanfang Hospital,Southern Medical University

Doctor Xie is affiliated with the Renal Division, Nanfang Hospital, Southern Medical University. She studied clinical medicine at the First Military Medical University and subsequently received her PhD degree from the Southern Medical University. 

Since 2004, Doctor Di Xie has held a position as a clinical nephrologist at the Southern Medical University. Her main research interests include optimizing RAS inhibitors treatments for patients with chronic kidney disease; screening and identifying novel risk factors and biomarkers for predicting the progression of chronic kidney disease; developing and evaluating new therapeutic approaches to halt the progression. To achieve these goals Dr. Xie is involved in various clinical trials and epidemiological studies and takes initiative to establish a large database of chronic kidney diseases.

Present Position
Associate Chief Physician
Renal Division, Nanfang Hospital, Southern Medical University
National Clinical Research Center for Kidney Disease
State Key Laboratory of Organ Failure Research
Contact: 86-20-61641595
E-mail: dixie81@163.com

Education
1997-2002: The First Military Medical University 
                  Major: Clinical Medicine
                  Degree: B.S.
2003-2004: The First Military Medical University  
                  Major: Internal Medicine (Nephrology)
                  Degree:  M.D. 
2007-2010: Southern Medical University   
                  Major: Internal Medicine (Nephrology)
                  Degree: Ph.D. 

Professional Experience:
2004- 2007: Resident, Renal Division, Nanfang Hospital, Southern Medical University
2008- 2016: Attending Physician, Renal Division, Nanfang Hospital, Southern Medical University
2017- present: Associate Chief Physician, Renal Division, Nanfang Hospital, Southern Medical University

Awards  
National Science and Technology Progress Award (the second prize), The clinical and basic research for preventing the progression of chronic kidney diseases. Awarded by the State Council of the P. R. China, 2007 (Di Xie contributed to this work as the 9th author)

Selected Research and Publications

1.Xie D, Yuan Y, Guo JN, Yang SL, Xu X, Wang Q, Li YB, Qin XH, Tang GF, Huo Y, Deng GP, Wu SJ, Wang BY, Zhang Q, Wang XB, Fang P, Wang H, Xu XP, Hou FF. Hyperhomocysteinemia predicts renal function decline: a prospective study in hypertensive adults. Sci Rep, 2015;5:16268. 

2.Xie D, Hou FF, Fu BL, Zhang X, Liang M. High level of proteinuria during treatment with renin-angiotensin inhibitors is a strong predictor of renal outcome in nondiabetic kidney disease. J Clin Pharmacol. 2011;51(7):1025-1034 

3.Xie D, Hou YQ, Hou FF, Zhang WR, Li Y, Guo ZG, Guo ZJ, Zhang X. Coronary stenting does not improve the long-term cardiovascular outcome of patients with mild to moderate renal insufficiency. Chin Med J 2009;122 (2):158-164 

4.Li Y, Xie D, Qin X, Tang G, Xing H, Li Z, Xu XP, Xu X, Hou F. Metabolic syndrome, but not insulin resistance, is associated with an increased risk of renal function decline. Clin Nutr. 2015; 34(2): 269-275. 

5.Wang Q, Xie D, Xu X, Qin X, Tang G, Wang B, Wang Y, Hou F, Xu X, Wang X. Blood pressure and renal function decline: a 7-year prospective cohort study in middle-aged rural Chinese men and women. J Hypertens. 2015; 33 (1):136-143. 

6.Hou FF, Xie D, Zhang X, Chen PY, Zhang WR, Liang M, Guo ZJ, Jiang JP. Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: A Randomized Controlled Study of Benazepril and Losartan in Chronic Renal Insufficiency. J Am Soc Nephrol 2007; 18(6):1889-1898

7.Hou FF, Zhang X, Zhang GH, Xie D, Chen PY, Zhang WR, Jiang JP, Liang M, Wang GB, Liu ZR, Geng RW. Efficacy and safety of benazepril for advanced chronic renal insufficiency. N Engl J Med 2006; 354(2):131-140